Researchers found that imidazole propionate, a molecule made of microorganisms, is an important factor in the development of atherosclerosis that opens new knees to early diagnosis and individualized treatment.
|A recent study published in Nature identifies propionate Imidazole (IMP), a metabolite obtained from intestinal microbicides, direct atherosclerosis driver and an emerging medical target.This quest not only expands the list of system performance, but also challenges the classic lipid, but also gives a disagreement, a struggle and a chant.Which can revolutionize both in diagnosis and treatment.
Even methods are available for avoiding atherosclerosis explain accidents, diagnosis, diagnosis, diagnosis of centerrical atherosclerotic fields.
At the human level, researchers showed a strong relationship between the presence of the IM plasma and the presence of atherosclerosis, using high -quality arterial images in two of their older colleagues (money and IGT).This comparison remained even after adjusting to the common risk factors, and more exposed to the bones and the disease used, and communication continued for common risk factors.Marongo was defined by the ⁸F-FDG collection.In the clinical context where the original and sensitive biomarker is needed immediately, IMP shows a promising diagnosis.
From the point of view, the details of the information as IM package Mortor-1 (I1R) received monolite, errors, errors of a lack of intermediate.What cannot be made in handorosclerosis in animals, but stops the development of the disease without improving the steps.
It was found in medical projects.Them represents all bioosal in atherols, which is more useful for patients and a lot of them coming out in violent policy
A critical view based on evidence |
Despite the power of results but there are tips that should be considered important:
• The constant companionship of Ali is not constituted.Even though the animal identifies a proprietion of the anterilersi to people.
• Characterization of bacterial species, which is associations with solar and vowel to produce a special stress that a person gives a special pressure.
• The clinical efficiency of the vital mark has not yet been verified in mixed risk groups or longitudinal studies.As for IM to be useful as an early sign, there will be a need to show its predictive ability in subsequent studies and not only its transient relationship with fixed disease.
• AGN192403 connection is not approved in a person or a long -term safety profile known.Although block I1R shows perspective results in mice, its therapeutic extrapolation will require a wide preclinic and clinical check.
|Conclusion |
MM EmtroSroserosiscis represents a new actor and a new actor connected to both diagnosis and medical experts.
This type of discovery invites us to expand the vision of cardiovascular disease in addition to cholesterol, to a more integrated approach, considering the microbiological system, inflammation and immunosomia are the main characters of atherosclerosis.
The study is mainly observed and based on mouse models.People who prove that reducing the level of cardiovascular results is not intervention data.Iimp -Isimp -Iim was measured in small human cohorts, and atheroprotective effects were made by its gemstones using MTOR1.Metabolieten Zoals de Itnen Worden Gekoppeld Aan Een Causaal, Onrafhankelijk en Wijzigbaar Risico Klinische Onderzoeken OP Grote Mensen, Blijven Ze Complementary, Net -Transformative Brevindingen.Hoewel de Be -be -be -be -be -be -be -be -be -be -be -be -be -be -be -be -be -be -be -be -be -be-be -be -be -be -be be -be -be -be -be -be -bewold van darmicrobiom kardiometabolishas risico onersteunen, vervangt ze de central rol van ldl -cholesterol niet uit from vervangen ze de pathogenic van atherosclerosis.
|* Specialist in internal drug consultancy.|