Key to increasing mortality from obesity, diseases

One study showed that obese people have a 70% risk of being hospitalized or dying from diseases.

According to a study of 540,000 people, obesity significantly increases the risk of hospitalization and death from most infectious diseases, including influenza, Covid-19, pneumonia, gastroenteritis, and urinary and respiratory infections.

The authors of the paper, published in The Lancet, confirm that people with this obesity condition have a 70% higher risk of developing severe forms and that, in the most severe cases, the probability of death or hospitalization increases threefold due to infections.

ໃນເວລາທີ່ນັກຄົ້ນຄວ້າໄດ້ວິເຄາະຜົນໄດ້ຮັບໃນທົ່ວໂລກໂດຍໃຊ້ຂໍ້ມູນຈາກການສຶກສາ Global Burden of Diseases, ພວກເຂົາເຈົ້າຄາດຄະເນວ່ານ້ໍາຫນັກເກີນຈະປະກອບສ່ວນໃຫ້ 0.6 ລ້ານຄົນໃນຈໍານວນ 5.4 ລ້ານຄົນເສຍຊີວິດຈາກພະຍາດຕິດຕໍ່ທີ່ບັນທຶກໄວ້ໃນປີ 2023. ການວິເຄາະນີ້ອະນຸຍາດໃຫ້ປະເທດປຽບທຽບ, ສະທ້ອນໃຫ້ເຫັນເຖິງຄວາມແຕກຕ່າງຂະຫນາດໃຫຍ່: ໃນສະຫະລັດ, ໃນສະຫະລັດ, ໃນສະຫະລັດ, ໃນສະຫະລັດ, ໃນສະຫະລັດແມ່ນ 4 ອັດຕາສ່ວນຂອງການເສຍຊີວິດຂອງຫນຶ່ງ.ຫວຽດນາມ ​ແມ່ນ​ປະມານ 1,2%.

Policies to promote weight loss

Co-author Solja Nyberg of the University of Helsinki says: "Obesy people are more likely to get sick or die from many infectious diseases. Due to the global increase in obesity rates, obesity-related hospitalizations and deaths will also increase, the researcher notes. She adds that it is urgent to promote policies that favor weight loss, such as healthy eating among obese people.facilitate exercise and vaccination.

The study combines data from two Finnish cohorts - with more than 67,000 adults - and Biobank in the UK - with 470,000 participants - followed for an average of 13 to 14 years.At the beginning of the study, their body mass index was assessed and the occurrence of infectious diseases was monitored over time.People with a BMI between 18.5 and 24.9 had an annual risk of serious infection of 1.1%, compared with 1.8% of the obese.

The risk increases steadily as body weight increases.People who are overweight (BMI ≥ 40) have a risk three times higher than people whose weight is considered healthy.The association applies to most of the ten common infections analyzed in detail: influenza, Covid-19, pneumonia, gastroenteritis, urinary tract and respiratory tract infections.It is not associated with severe cases of HIV or tuberculosis.

Weak immune system

"Our finding that obesity is a risk factor for various infectious diseases suggests that a common biological mechanism is involved," said Mika Kivimäki, from University College London and leader of the work.According to researchers, it is believed that obesity impairs the ability of the immune system to protect itself from bacteria, viruses, parasites or fungi, which leads to very serious conditions.

Kivimäki also notes that evidence from clinical trials supports this theory, as excess weight appears to reduce the risk of serious infections.

Figures from the Global Burden of Disease study reveal huge differences between countries: from 1.2% of deaths related to obesity in Vietnam to 25.7% in the United States and 17.4% in the United Kingdom. Sarah Ahmadi-Abhari from Imperial College London warns, "these figures give an idea of ​​the problem, but they should be interpreted with caution because the data are not always good, especially in countries with limited resources."

Solja T Nyberg et al.Obesity and risk of severe disease: a multicohort study with global burden estimates.Lancet, 2026.

Source: The Lancet

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